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Volume 31 , Issue 3
May/June 2011
Pages 227-235

The Clinical and Histologic Efficacy of Xenograft Granules for Maxillary Sinus Floor Augmentation

Myron Nevins, DDS/Marcelo Camelo, DDS/Nicola De Angelis, DDS/ James J. Hanratty, DDS/Wahn G. Khang, DMD/Jong-Jin Kwon, DDS, PhD/ Giulio Rasperini, DDS/Isabella Rocchietta, DDS/Peter Schupbach, PhD/ David M. Kim, DDS, DMSc

PMID: 21556379
DOI: 10.11607/prd.00.0981

The objective of this study was to investigate the potential of xenograft (cancellous bovine bone) granules to form vital bone in non-natural bone-forming areas of maxillary sinuses. Fourteen sinus augmentations were performed in 14 patients. Surgical outcomes were uneventful, and sufficient radiopaque volume was present radiographically to place dental implants in all sites. Clinical reentry at 6 months revealed bone formation at the osteotomy site. Histologic evaluation of the obtained bone cores revealed that xenograft granules were integrated and surrounded by woven bone and lamellar bone that were in close contact with the particles. The average percentage of newly formed bone at 6 months was 27.5% ± 8.9%. Vital bone formation using the xenograft granules was supported by both clinical and histologic evidence. (Int J Periodontics Restorative Dent 2011;31:227–235.)

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